Our vaginal rings are made out of ethylene-vinyl-acetate; a polymer which is widely used in medical products including FDA approved vaginal rings.  We use a matrix design in which the drug and polymer are interspersed throughout the entire ring.  This design allows for the delivery of hydrophobic and hydrophilic molecules as well as proteins and other large molecules.  We have also designed segmented rings where each segment contains a different drug, uniquely formulated for its optimal pharmacokinetics, but with the ability to be delivered in a single device. 

We are targeting women’s reproductive endocrinology disorders initially.   Follow-on applications include diabetes, obesity, and infectious disease.

We were founded by William Crowley, Professor of Medicine at Harvard Medical School and Robert Langer, Institute Professor of MIT